Function of propionyl chloride 79-03-8

October 14, 2024

Uses of propionyl chloride ‌ The main uses of propionyl chloride include the following aspects ‌ :

Organic synthesis ‌ : propionyl chloride is often used as a propionylation reagent in organic synthesis. It is an intermediate in the preparation of various propionic acid derivatives, such as phenylacetone ‌.

‌ Pharmaceutical industry ‌ : propionyl chloride is used in the pharmaceutical industry in the production of antiepileptic drugs, cholinol, antiadrenergic drugs, etc. For example, the antiepileptic drugs belladonetoin, cholineol and methoxyamine hydrochloride, etc ‌.

Pesticide production ‌ : Propionyl chloride is often used as a raw material of the herbicide paspalum in pesticide production ‌.

‌ Other applications ‌ : propionyl chloride is also used in the synthesis of medicine, dyes, pesticides and other important intermediates ‌.

‌ Propionyl chloride synthesis method ‌ mainly includes the following two:

Acyl chlorination ‌ : 2-chloropropionyl chloride is synthesized from 2-chloropropionic acid under the action of phosgene, sulfoxide chloride, phosphorus trichloride and other acyl chlorination reagents. Because phosgene is a highly toxic gas and the industry entry threshold is high, sulfoxide chloride and phosphacyl trichloride chloride methods will cause environmental pollution and equipment corrosion ‌.

‌ Propionyl chloride chloride process ‌ : this method has the advantages of simple reaction and stable product quality, and has attracted much attention ‌.

‌ Storage method ‌ : propionyl chloride should be sealed, heat and moisture proof, stored and transported in accordance with the provisions of toxic chemicals ‌.